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Probiotic

Bacillus coagulans IS-2

Bacillus coagulans Unique IS-2®

Dose range

100mg200mg
Spore-forming — survives stomach acid
Published clinical research on IS-2
Stable without refrigeration
Vegan & gluten-free
Bacillus coagulans IS-2

What is Bacillus coagulans IS-2?

A spore-forming probiotic strain that is shelf-stable without refrigeration. The Unique IS-2® strain does not require cold-chain storage, making it suitable for the microgranule format.

Why Bacillus coagulans Unique IS-2®?

Bacillus coagulans Unique IS-2 is a spore-forming strain that survives stomach acid and bile intact — unlike most probiotic strains that are largely destroyed before reaching the intestine — with published clinical studies confirming safety and tolerability.

About Bacillus coagulans IS-2

Spore-forming survival

Unlike most probiotic strains, Bacillus coagulans forms dormant spores that resist stomach acid, bile and heat. The IS-2 spores germinate into active vegetative cells once past the stomach.

Clinically studied strain

Bacillus coagulans Unique IS-2® is backed by published clinical studies confirming safety and tolerability. It is one of the most well-characterised spore-forming probiotic strains available.

Shelf-stable without refrigeration

The spore form is stable at room temperature — unlike many Lactobacillus and Bifidobacterium strains that require cold-chain storage. Your formula can be stored at room temperature without affecting probiotic viability.

What does the research say?

The studies cited below are published peer-reviewed research. They do not constitute health claims for this product and are presented for informational purposes only.

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Common questions about Bacillus coagulans IS-2

Bacillus coagulans IS-2 is one of 31 compounds your formula can draw from.

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